Article
Comparison of the rate and size of HIV-1 viral load blips with Roche COBAS TaqMan HIV-1 versions 1.0 and 2.0 and implications for patient management.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Apr 2012
Garrett Nigel J, Apea Vanessa, Nori Achyuta, Ushiro-Lumb Ines, Oliver Anthony R, Baily Guy, Clark Duncan A
Abstract excerpt
BACKGROUND: The Roche COBAS TaqMan HIV-1 version 1.0 (v1.0) real-time PCR test detects more low level viral loads (VL) compared to the previous Roche Amplicor version 1.5 assay. Due to under-quantification issues, the Roche TaqMan HIV-1 version 2.0 (v2.0) was introduced in 2009. Controversy remai...
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