Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

BRAP Activates Inflammatory Cascades and Increases the Risk for Carotid Atherosclerosis.

Molecular medicine (Cambridge, Mass.) - 1 Jan 2000

Liao Yi-Chu, Wang Yung-Song, Guo Yuh-Cherng, Ozaki Kouichi, Tanaka Toshihiro, Lin Hsiu-Fen, Chang Ming-Hong, Chen Ku-Chung, Yu Ming-Lung, Sheu Sheng-Hsiung, Juo Suh-Hang Hank

Abstract excerpt

The BRCA-1 associated protein gene (BRAP) was recently identified as a susceptibility gene for myocardial infarction (MI). In the present study we aimed to decipher the association between the BRAP polymorphism and carotid atherosclerosis and the mechanism underlying its proatherogenic effect. A total of 1749 stroke/MI-free volunteers received carotid ultrasonic examinations for the measurement of intima-medial...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carotid Artery Diseases
Share to Chlorocebus aethiops

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to COS Cells

Share to I-kappa B Proteins

Share to Lipopolysaccharides

Share to Myocytes, Smooth Muscle

Share to Tunica Intima

Share to Tunica Media

Source

Open in PubMed Open full text

Identifiers

PMID: 21670849
DOI: 10.2119/molmed.2011.00043
PMCID: PMC3188876

Genes

BRAP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

BRAP Activates Inflammatory Cascades and Increases the Risk for Carotid Atherosclerosis.PMID 21670849Read ↗

SNPs in BRAP associated with risk of myocardial infarction in Asian populations.Semantic proximity Read ↗

Lack of association between a functional variant of the BRCA-1 related associated protein (BRAP) gene and ischemic stroke.Semantic proximity Read ↗

Lipid-induced epigenomic changes in human macrophages identify a coronary artery disease-associated variant that regulates PPAP2B Expression through Altered C/EBP-beta binding.Semantic proximity Read ↗

Genome-wide association analysis of soluble ICAM-1 concentration reveals novel associations at the NFKBIK, PNPLA3, RELA, and SH2B3 loci.Semantic proximity Read ↗

Genetic and environmental risk factors for atherosclerosis regulate transcription of phosphatase and actin regulating gene PHACTR1.Semantic proximity Read ↗

Molecular biology of atherosclerosis.Semantic proximity Read ↗

BIRC6 Is Associated with Vulnerability of Carotid Atherosclerotic Plaque.Semantic proximity Read ↗

ICAM-1 molecular mechanism and genome wide SNP's association studies.Semantic proximity Read ↗

Interleukin-18/interleukin-18 binding protein signaling modulates atherosclerotic lesion development and stability.Semantic proximity Read ↗

BRIP1 variations analysis reveals their relative importance as genetic susceptibility factor for cervical cancer.Semantic proximity Read ↗

Functional Analysis of a Carotid Intima-Media Thickness Locus Implicates BCAR1 and Suggests a Causal Variant.Semantic proximity Read ↗

The single nucleotide polymorphisms in BRAP decrease the risk of metabolic syndrome in a Chinese young adult population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.