Article
Natural and artificial mutants of the human 2,3-bisphosphoglycerate as a tool for the evaluation of structure-function relationships.
Biomedica biochimica acta - 1 Jan 1990
Garel M C, Lemarchandel V, Prehu M O, Calvin M C, Arous N, Rosa R, Rosa J, Cohen-Solal M
Abstract excerpt
2,3-bisphosphoglycerate mutase is a multifunctional enzyme which catalyses in red blood cells the synthesis and the degradation of 2,3-bisphosphoglycerate, the allosteric effector of hemoglobin. In order to study the structure-function relationships in BPGM, an expression vector was constructed w...
Topics
- 2,3-Diphosphoglycerate
- Amino Acid Sequence
- Base Sequence
- Bisphosphoglycerate Mutase
- Cloning, Molecular
- DNA
- Diphosphoglyceric Acids
- Escherichia coli
- Gene Expression
- Humans
- Molecular Sequence Data