Article
Aging and photo-aging DNA repair phenotype of skin cells-evidence toward an effect of chronic sun-exposure.
Mutation research - 1 Aug 2012
Prunier Chloé, Masson-Genteuil Gwénaëlle, Ugolin Nicolas, Sarrazy Fanny, Sauvaigo Sylvie
Abstract excerpt
Several studies have demonstrated the deleterious effect of aging on the capacity of cells to repair their DNA. However, current existing assays aimed at measuring DNA repair address only a specific repair step dedicated to the correction of a specific DNA lesion type. Consequently they provide no information regarding the repair pathways that handle other types of lesions. In addition to aging, consequences of...
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