Article
Gene expression and miR profiles of human corneal fibroblasts in response to dexamethasone.
Investigative ophthalmology & visual science - 21 Sept 2011
Liu Lei, Walker Elizabeth A, Kissane Stephen, Khan Imran, Murray Philip I, Rauz Saaeha, Wallace Graham R
Abstract excerpt
PURPOSE: Dexamethasone (DEX) is commonly used as a therapeutic agent for various ocular inflammatory diseases; however, its effect on resident naive cells is unknown. In this study, genome microarray and microRNA (miR) analyses were used to evaluate the global gene and miR expression of human corneal fibroblasts (HKFs) in response to treatment with DEX. METHODS: Primary HKFs from three donors were treated with...
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