Article
A functional variant in ZNF512B is associated with susceptibility to amyotrophic lateral sclerosis in Japanese.
Human molecular genetics - 15 Sept 2011
Iida Aritoshi, Takahashi Atsushi, Kubo Michiaki, Saito Susumu, Hosono Naoya, Ohnishi Yozo, Kiyotani Kazuma, Mushiroda Taisei, Nakajima Masahiro, Ozaki Kouichi, Tanaka Toshihiro, Tsunoda Tatsuhiko, Oshima Shuichi, Sano Motoki, Kamei Tetsumasa, Tokuda Torao, Aoki Masashi, Hasegawa Kazuko, Mizoguchi Koichi, Morita Mitsuya, Takahashi Yuji, Katsuno Masahisa, Atsuta Naoki, Watanabe Hirohisa, Tanaka Fumiaki, Kaji Ryuji, Nakano Imaharu, Kamatani Naoyuki, Tsuji Shoji, Sobue Gen, Nakamura Yusuke, Ikegawa Shiro
Abstract excerpt
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by the selective loss of motor neurons. Several susceptibility genes for ALS have been reported; however, ALS etiology and pathogenesis remain largely unknown. To identify further ALS-susceptibility genes, we conducted a large-scale case-control association study using gene-based tag single-nucleotide polymorphisms (SNPs). A...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.