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Article

The expression and phosphorylation of acid sensing ion channel 1a in the brain of a mouse model of phenylketonuria.

The International journal of neuroscience - 1 Jul 2011

Liang Lili, Gu Xuefan, Li Duan, Lu Lihua

Abstract excerpt

The acid-sensing ion channel 1a (ASIC1a) is a proton-gated cation channel enriched in the mammalian brain. Recent studies suggest its diverse roles in ischemic acidosis, neurodegenerative diseases, and cognitive processes. Phenylketonuria (PKU) is the most commonly inherited defect in amino acid metabolism. Many facts make ASIC1a appear to be highly related to PKU. In this study, we explored the effect of PKU on...

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Identifiers

PMID: 21663378
DOI: 10.3109/00207454.2011.568655

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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