Article
A miRNA-492 binding-site polymorphism in BSG (basigin) confers risk to psoriasis in central south Chinese population.
Human genetics - 1 Dec 2011
Wu Li-Sha, Li Fang-Fang, Sun Liang-Dan, Li Dai, Su Juan, Kuang Ye-Hong, Chen Gang, Chen Xiao-Ping, Chen Xiang
Abstract excerpt
Psoriasis (PS; MIM#177900) is a chronic inflammatory immune-mediated skin disorder. Although the disease is believed to be caused by a combination of genetic, immunologic and environmental factors, its complete etiology has not been fully understood. Here, we focused on the BSG (MIM#109480), a member of the immunoglobulin superfamily expressed ubiquitously in circulating immune cell populations. We observed that...
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