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Article

MixupMapper: correcting sample mix-ups in genome-wide datasets increases power to detect small genetic effects.

Bioinformatics (Oxford, England) - 1 Aug 2011

Westra Harm-Jan, Jansen Ritsert C, Fehrmann Rudolf S N, te Meerman Gerard J, van Heel David, Wijmenga Cisca, Franke Lude

Abstract excerpt

MOTIVATION: Sample mix-ups can arise during sample collection, handling, genotyping or data management. It is unclear how often sample mix-ups occur in genome-wide studies, as there currently are no post hoc methods that can identify these mix-ups in unrelated samples. We have therefore developed an algorithm (MixupMapper) that can both detect and correct sample mix-ups in genome-wide studies that study gene...

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PMID: 21653519
DOI: 10.1093/bioinformatics/btr323

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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