Article
Alternative splicing of the Anopheles gambiae Dscam gene in diverse Plasmodium falciparum infections.
Malaria journal - 8 Jun 2011
Smith Paul H, Mwangi Jonathan M, Afrane Yaw A, Yan Guiyun, Obbard Darren J, Ranford-Cartwright Lisa C, Little Tom J
Abstract excerpt
BACKGROUND: In insects, including Anopheles mosquitoes, Dscam (Down syndrome cell adhesion molecule) appears to be involved in phagocytosis of pathogens, and shows pathogen-specific splice-form expression between divergent pathogen (or parasite) types (e.g. between bacteria and Plasmodium or between Plasmodium berghei and Plasmodium falciparum). Here, data are presented from the first study of Dscam expression in...
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