Article
Molecular chaperones as a common set of proteins that regulate the invasion phenotype of head and neck cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Jul 2011
Chiu Ching-Chi, Lin Chien-Yu, Lee Li-Yu, Chen Yin-Ju, Lu Ya-Ching, Wang Hung-Ming, Liao Chun-Ta, Chang Joseph Tung-Chieh, Cheng Ann-Joy
Abstract excerpt
PURPOSE: The goal of this study was to establish a common set of molecules that regulate cell invasion in head and neck cancer (HNC). EXPERIMENTAL DESIGN: Five invasive sublines derived from HNC cell lines were established using the Matrigel selection method. Proteomic technology, MetaCore algorithm, and reverse transcriptase-PCR methods were used to search for molecules that contribute to the invasion phenotype....
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