Article
Cytokine gene polymorphism and asthma susceptibility, progress and control level.
Molecular biology reports - 1 Feb 2012
Daneshmandi Saeed, Pourfathollah Ali Akbar, Pourpak Zahra, Heidarnazhad Hasan, Kalvanagh Parisa Amir
Abstract excerpt
Asthma is a multifactor inflammatory disorder, and its management requires understanding of its various pathogenesis and control mechanisms. Cytokines and other inflammatory mediators are important factors in asthma pathophysiology. In this study, we evaluated the role of cytokine polymorphisms in the asthma susceptibility, progress, control, and lung functions. IL-4-C590T polymorphism by PCR-RFLP method, IFN-γ...
Topics
- Adult
- Analysis of Variance
- Asthma
- Cytokines
- Enzyme-Linked Immunosorbent Assay
- Female
- Genetic Predisposition to Disease
- Humans
- Interferon-gamma
- Interleukin-4
- Interleukin-6
- Male
- Maximal Midexpiratory Flow Rate
- Middle Aged
