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Article

Coupled, circumferential motions of the cell wall synthesis machinery and MreB filaments in B. subtilis.

Science (New York, N.Y.) - 8 Jul 2011

Garner Ethan C, Bernard Remi, Wang Wenqin, Zhuang Xiaowei, Rudner David Z, Mitchison Tim

Abstract excerpt

Rod-shaped bacteria elongate by the action of cell wall synthesis complexes linked to underlying dynamic MreB filaments. To understand how the movements of these filaments relate to cell wall synthesis, we characterized the dynamics of MreB and the cell wall elongation machinery using high-precision particle tracking in Bacillus subtilis. We found that MreB and the elongation machinery moved circumferentially...

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Identifiers

PMID: 21636745
DOI: 10.1126/science.1203285
PMCID: PMC3235694

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