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Article

RodZ acts through MreBCD to activate the elongasome in Escherichia coli.

Journal of bacteriology - 17 Sept 2026

Zhan Rui, Gong Han, Li Ying, Cui Yuanyuan, Chen Xiangdong, Lutkenhaus Joe, Du Shishen

Abstract excerpt

Most bacteria are surrounded by a peptidoglycan (PG) matrix that maintains cell shape and provides protection against turgor pressure. In many rod-shaped bacteria, synthesis of PG along the cell cylinder is organized by the elongasome, also called the rod complex, which consists of six highly conserved proteins, including the actin-like MreB, the PG synthase complex RodA-PBP2, and three regulatory membrane...

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Topics

Escherichia coli Proteins
Escherichia coli
Peptidoglycan
Cytoskeletal Proteins
Mutation
Bacterial Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Cell Wall

Membrane Proteins

Penicillin-Binding Proteins

Source

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Identifiers

PMID: 42578761
DOI: 10.1128/jb.00594-25
PMCID: PMC13584716

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 24 Oct 2026.

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