Article
Absence seizures associated with efavirenz initiation.
The Pediatric infectious disease journal - 1 Nov 2011
Strehlau Renate, Martens Leigh, Coovadia Ashraf, Dandara Collet, Norman Jennifer, Maisel Julia, Kuhn Louise, Abrams Elaine J
Abstract excerpt
Efavirenz, used in treating pediatric human immunodeficiency virus infection, has central nervous system side effects. We report on a 5-year-old girl with perinatally acquired human immunodeficiency virus infection, presenting with new onset absence seizures after starting treatment with efavirenz. Plasma efavirenz values were above therapeutic range. The child was homozygous for the CYP2B6-516T/T genotype, which...
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