[The genetics of dementias, Part 3: a molecular basis for the multifactorial inheritance of sporadic Alzheimer's disease].

Abstract excerpt

The majority of Alzheimer's disease cases, i.e. more than 85% of the whole population of patients, can be referred to as the sporadic form of the disease, with a negative family history and complex inheritance. As the genetic background of sporadic Alzheimer's disease is still largely unknown., strategies based on individual genetic risk profiling for either early prediction of the disease or its therapy and...

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