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The truth about genetic variation in the serotonin transporter gene and response to stress and medication

31 May 2011

Abstract excerpt

The question of whether a functional variant in the promoter of the serotonin transporter gene (5-HTTLPR) influences response to adversity and/or antidepressants has generated great interest and controversy. A review of the literature suggests that the issue is complicated by differences in methodology and sample ethnicity. When these confounders are accounted for, there probably is a real, if small, effect of...

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PMID: 21628702
DOI: 10.1192/bjp.bp.110.085225

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