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Article

Low CTLA-4 expression in CD4+ helper T-cells in patients with fulminant type 1 diabetes.

Immunology letters - 30 Sept 2011

Haseda Fumitaka, Imagawa Akihisa, Murase-Mishiba Yuko, Sano Hiroyuki, Hirano-Kuwata Suzue, Ueda Hironori, Terasaki Jungo, Hanafusa Toshiaki

Abstract excerpt

Fulminant type 1 diabetes is a novel subtype of type 1 diabetes characterized by a remarkably abrupt onset of insulin-deficient hyperglycemia. An accelerated immune reaction has been suggested as the cause of markedly rapid beta cell loss in this disease, but the precise mechanism has not been clarified. We analyzed the expression of cytotoxic T lymphocyte antigen 4 (CTLA-4) in CD4(+) helper T-cells in 16...

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Identifiers

PMID: 21620894
DOI: 10.1016/j.imlet.2011.05.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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