Article
Smoking, dietary betaine, methionine, and vitamin D in monozygotic twins with discordant macular degeneration: epigenetic implications.
Ophthalmology - 1 Jul 2011
Seddon Johanna M, Reynolds Robyn, Shah Heeral R, Rosner Bernard
Abstract excerpt
OBJECTIVE: We evaluated monozygotic twin pairs with discordant age-related macular degeneration (AMD) phenotypes to assess differences in behavioral and nutritional factors. DESIGN: Case series. PARTICIPANTS: Caucasian male twin pairs from the United States Twin Study of Macular Degeneration. METHODS: Twin pairs were genotyped to confirm monozygosity. Ocular characteristics were evaluated based on fundus...
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