Article
Age related macular degeneration in monozygotic twins and their spouses in Iceland.
Acta ophthalmologica Scandinavica - 1 Aug 1999
Gottfredsdottir M S, Sverrisson T, Musch D C, Stefánsson E
Abstract excerpt
PURPOSE: To examine the importance of genetic factors in age-related macular degeneration by using a twin study to compare the concordance of age-related macular degeneration in monozygotic twin pairs and their spouses. METHODS: This was a prospective study that included 50 twin pairs and 47 spouses. Zygosity was determined by genetic laboratory testing. Macular findings were graded based on the grading system...
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