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Article

Role of free radicals produced during the metabolism of mitomycin C in Escherichia coli inactivation.

Xenobiotica; the fate of foreign compounds in biological systems - 1 May 1990

Schiavano G F, Brandi G, Salvaggio L, Cattabeni F C, Cantoni O

Abstract excerpt

1. The primary objective of this study was to assess whether reactive oxygen species produced during the metabolism of mitomycin C are responsible for, or contribute to, the induction of the cytotoxic response. 2. Escherichia coli wild-type and superoxide dismutase mutants were grown either anoxically or euoxically, in K medium or minimal glucose medium, and treated with mitomycin C in K medium or M9 salts. The...

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PMID: 2161589
DOI: 10.3109/00498259009046869

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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