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Article

The divergence between two oncogenic Herpesvirus saimiri strains in a genomic region related to the transforming phenotype.

Virology - 1 Jun 1990

Biesinger B, Trimble J J, Desrosiers R C, Fleckenstein B

Abstract excerpt

Herpesvirus saimiri strains can be divided into at least three subgroups (A, B, C) based on sequence divergence at the left end of viral unique sequence DNA. Strains of subgroups A and C are highly oncogenic and readily transform simian T-lymphocytes in vitro to interleukin-2 independent growth, while subgroup B strains do not. A left terminal reading frame of a H. saimiri subgroup A strain was shown previously...

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Identifiers

PMID: 2161148
DOI: 10.1016/0042-6822(90)90020-r

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DHFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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