The divergence between two oncogenic Herpesvirus saimiri strains in a genomic region related to the transforming phenotype.

doi:10.1016/0042-6822(90)90020-r

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Article

The divergence between two oncogenic Herpesvirus saimiri strains in a genomic region related to the transforming phenotype.

Virology - 1 Jun 1990

Biesinger B, Trimble J J, Desrosiers R C, Fleckenstein B

Abstract excerpt

Herpesvirus saimiri strains can be divided into at least three subgroups (A, B, C) based on sequence divergence at the left end of viral unique sequence DNA. Strains of subgroups A and C are highly oncogenic and readily transform simian T-lymphocytes in vitro to interleukin-2 independent growth,...

Topics

Amino Acid Sequence
Animals
Base Sequence
Cell Line
Cell Transformation, Neoplastic
Cell Transformation, Viral
Cloning, Molecular
DNA, Viral
Herpesvirus 2, Saimiriine
Molecular Sequence Data
Oncogene Proteins, Viral
Phenotype
Plasmids
Polymerase Chain Reaction
RNA, Small Nuclear
RNA, Viral
Sequence Homology, Nucleic Acid
Tetrahydrofolate Dehydrogenase

Source

Open in PubMed

Identifiers

PMID: 2161148
DOI: 10.1016/0042-6822(90)90020-r

Genes

DHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2161148-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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