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Article

Mangiferin, an anti-HIV-1 agent targeting protease and effective against resistant strains.

Molecules (Basel, Switzerland) - 24 May 2011

Wang Rui-Rui, Gao Yue-Dong, Ma Chun-Hui, Zhang Xing-Jie, Huang Cheng-Gang, Huang Jing-Fei, Zheng Yong-Tang

Abstract excerpt

The anti-HIV-1 activity of mangiferin was evaluated. Mangiferin can inhibit HIV-1(Ⅲ)(B) induced syncytium formation at non-cytotoxic concentrations, with a 50% effective concentration (EC₅₀) at 16.90 μM and a therapeutic index (TI) above 140. Mangiferin also showed good activities in other labora...

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Share to Anti-HIV Agents
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Share to Drug Resistance, Viral

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Leukocytes, Mononuclear

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Share to Protein Binding

Source

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Identifiers

PMID: 21610656
DOI: 10.3390/molecules16054264
PMCID: PMC6263262

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21610656-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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