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Article

Significantly increased risk of carotid atherosclerosis with arsenic exposure and polymorphisms in arsenic metabolism genes.

Environmental research - 1 Aug 2011

Hsieh Yi-Chen, Lien Li-Ming, Chung Wen-Ting, Hsieh Fang-I, Hsieh Pei-Fan, Wu Meei-Maan, Tseng Hung-Pin, Chiou Hung-Yi, Chen Chien-Jen

Abstract excerpt

Individual susceptibility to arsenic-induced carotid atherosclerosis might be associated with genetic variations in arsenic metabolism. The purpose of this study is to explore the interaction effect on risk of carotid atherosclerosis between arsenic exposure and risk genotypes of purine nucleoside phosphorylase (PNP), arsenic (+3) methyltransferase (As3MT), and glutathione S-transferase omega 1 (GSTO1) and omega...

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Source

Identifiers

PMID: 21605854
DOI: 10.1016/j.envres.2011.05.003

Genes

PNP
GSTO1
GSTO2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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