Article
The use of a genotypic marker to demonstrate clonal dominance during the growth and metastasis of a human breast carcinoma in nude mice.
International journal of cancer - 15 May 1990
Price J E, Bell C, Frost P
Abstract excerpt
When a mixture of 11 clones of a human breast carcinoma (MDA-MB-435)--each clone transfected with pSV2neo and identified as having a unique insertion site of the gene--was injected into nude mice, the resulting tumors were found to contain only one clone (Neo 24). This clone, identified by the un...
Topics
- Animals
- Breast Neoplasms
- Cell Division
- Cell Line
- Clone Cells
- DNA Transposable Elements
- DNA, Bacterial
- DNA, Neoplasm
- Drug Resistance, Microbial
- Female
- Genetic Markers
- Genotype
- Humans
- Mice
- Mice, Nude
- Neomycin
- Neoplasm Metastasis
- Neoplasm Transplantation