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Article

PAX6 haplotypes are associated with high myopia in Han chinese.

PloS one - 12 May 2011

Jiang Bo, Yap Maurice K H, Leung Kim Hung, Ng Po Wah, Fung Wai Yan, Lam Wai Wa, Gu Yang-Shun, Yip Shea Ping

Abstract excerpt

BACKGROUND: The paired box 6 (PAX6) gene is considered as a master gene for eye development. Linkage of myopia to the PAX6 region on chromosome 11p13 was shown in several studies, but the results for association between myopia and PAX6 were inconsistent so far. METHODOLOGY/PRINCIPAL FINDINGS: We genotyped 16 single nucleotide polymorphisms (SNPs) in the PAX6 gene and its regulatory regions in an initial study for...

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Source

Open in PubMed Open full text

Identifiers

PMID: 21589860
DOI: 10.1371/journal.pone.0019587
PMCID: PMC3093386

Genes

PAX6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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