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Article

Association of PAX6 polymorphisms with high myopia in Han Chinese nuclear families.

Investigative ophthalmology & visual science - 1 Jan 2009

Han Wei, Leung Kim Hung, Fung Wai Yan, Mak Joey Y Y, Li Yu Min, Yap Maurice K H, Yip Shea Ping

Abstract excerpt

PURPOSE: The paired box 6 (PAX6) gene is critical to eye development. Based on prior linkage evidence, this study was conducted to investigate the association of PAX6 polymorphisms with high myopia in a Han Chinese population. METHODS: Tag single nucleotide polymorphisms (tSNPs) in the PAX6 locus were selected based on HapMap data, and other polymorphisms in its functional regions were also identified. Both tSNPs...

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Source

Identifiers

PMID: 19124844
DOI: 10.1167/iovs.07-0813

Genes

PAX6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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