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Phosphoethanolamine Modification of Lipid A in Colistin-Resistant Variants of Acinetobacter baumannii Mediated by the pmrAB Two-Component Regulatory System

17 May 2011

Abstract excerpt

Colistin resistance is rare in Acinetobacter baumannii, and little is known about its mechanism. We investigated the role of PmrCAB in this trait, using (i) resistant and susceptible clinical strains, (ii) laboratory-selected mutants of the type strain ATCC 19606 and of the clinical isolate ABRIM, and (iii) a susceptible/resistant pair of isogenic clinical isolates, Ab15/133 and Ab15/132, isolated from the same...

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Antibiotic Resistance in Bacteria
Drug Transport and Resistance Mechanisms
Pneumonia and Respiratory Infections

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 21576434
DOI: 10.1128/aac.00079-11

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