Article
Comparison of thermosensitive alleles of the CDC25 gene involved in the cAMP metabolism of Saccharomyces cerevisiae.
Genetics - 1 Apr 1990
Petitjean A, Hilger F, Tatchell K
Abstract excerpt
The CDC25 gene from Saccharomyces cerevisiae is an essential component of the RAS-adenylate cyclase pathway. Genetic and biochemical evidence has led to the proposal that the gene product may act upstream of RAS, possibly as a guanine nucleotide exchange factor. We report here the cloning, sequen...
Topics
- Adenylyl Cyclases
- Alleles
- Amino Acid Sequence
- Base Sequence
- Cell Cycle Proteins
- Cloning, Molecular
- Cyclic AMP
- Fungal Proteins
- Genes, Fungal
- Genes, ras
- Molecular Sequence Data
- Mutation
- Phenotype
- Restriction Mapping
- Saccharomyces cerevisiae
- Suppression, Genetic
- Temperature
- ras-GRF1