Article
Effectiveness and causes for failure of surveillance of CDKN2A-mutated melanoma families.
Journal of the American Academy of Dermatology - 1 Aug 2011
van der Rhee Jasper I, de Snoo Femke A, Vasen Hans F A, Mooi Wolter J, Putter Hein, Gruis Nelleke A, Kukutsch Nicole A, Bergman Wilma
Abstract excerpt
BACKGROUND: For more than 25 years families with an increased susceptibility to melanoma have been under surveillance at our institution. OBJECTIVE: We sought to investigate the effectiveness of surveillance for CDKN2A-mutated families and causes for failure of the program in patients with more advanced tumors. METHODS: In a retrospective case-control study, Breslow thickness of melanomas diagnosed in relatives...
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