Article
The association of HLA-DQB1, -DQA1 and -DPB1 alleles with anti- glomerular basement membrane (GBM) disease in Chinese patients.
BMC nephrology - 13 May 2011
Luo Huan, Chen Min, Cui Zhao, Yang Rui, Xu Peng-Cheng, Zhou Xu-Jie, Zhao Ming-Hui
Abstract excerpt
BACKGROUND: Human leukocyte antigen (HLA) alleles are associated with many autoimmune diseases, including anti-glomerular basement membrane (GBM) disease. In our previous study, it was demonstrated that HLA-DRB1*1501 was strongly associated with anti-GBM disease in Chinese. However, the association of anti-GBM disease and other HLA class II genes, including HLA-DQB1, -DQA1,-DPB1 alleles, has rarely been...
Topics
- Adolescent
- Adult
- Aged
- Aged, 80 and over
- Alleles
- Anti-Glomerular Basement Membrane Disease
- Asian People
- Case-Control Studies
- China
- Exons
- Female
- Genetic Predisposition to Disease
- HLA-DP Antigens
- HLA-DP beta-Chains