Article
PoPMuSiC 2.1: a web server for the estimation of protein stability changes upon mutation and sequence optimality.
BMC bioinformatics - 13 May 2011
Dehouck Yves, Kwasigroch Jean Marc, Gilis Dimitri, Rooman Marianne
Abstract excerpt
BACKGROUND: The rational design of modified proteins with controlled stability is of extreme importance in a whole range of applications, notably in the biotechnological and environmental areas, where proteins are used for their catalytic or other functional activities. Future breakthroughs in medical research may also be expected from an improved understanding of the effect of naturally occurring disease-causing...
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