Article
Organ-specific alterations in fatty acid de novo synthesis and desaturation in a rat model of programmed obesity.
Lipids in health and disease - 11 May 2011
Yee Jennifer K, Lee Wai-Nang P, Han Guang, Ross Michael G, Desai Mina
Abstract excerpt
BACKGROUND: Small for gestational age (SGA) leads to increased risk of adult obesity and metabolic syndrome. Offspring exposed to 50% maternal food restriction in utero are born smaller than Controls (FR), catch-up in growth by the end of the nursing period, and become obese adults. The objective of the study was to determine stearoyl-CoA desaturase activity (SCD1) and rates of de novo fatty acid synthesis in...
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