Article
Catch-up growth following intra-uterine growth-restriction programmes an insulin-resistant phenotype in adipose tissue.
International journal of obesity (2005) - 1 Aug 2013
Berends L M, Fernandez-Twinn D S, Martin-Gronert M S, Cripps R L, Ozanne S E
Abstract excerpt
BACKGROUND: It is now widely accepted that the early-life nutritional environment is important in determining susceptibility to metabolic diseases. In particular, intra-uterine growth restriction followed by accelerated postnatal growth is associated with an increased risk of obesity, type-2 diabetes and other features of the metabolic syndrome. The mechanisms underlying these observations are not fully...
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