ENPP1/PC-1 gene K121Q polymorphism is associated with obesity in European adult populations: evidence from a meta-analysis involving 24,324 subjects.

doi:10.3967/0895-3988.2011.02.015

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Article

ENPP1/PC-1 gene K121Q polymorphism is associated with obesity in European adult populations: evidence from a meta-analysis involving 24,324 subjects.

Biomedical and environmental sciences : BES - 1 Apr 2011

Wang RuoQi, Zhou DongHao, Xi Bo, Ge XiuShan, Zhu Ping, Wang Bo, Zhou MingAi, Huang YuBei, Liu JunTing, Yu Yang, Wang ChunYu

Abstract excerpt

OBJECTIVE: Findings from the previous studies have suggested a relationship between ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP-1) or plasma cell membrane glycoprotein 1 (PC-1) gene single nucleotide polymorphism (K121Q, rs1044498) and genetic susceptibility to obesity. However, such relationship is not reproduced by some currently available studies. In this context, the present study is aimed to...

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PMID: 21565692
DOI: 10.3967/0895-3988.2011.02.015

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ENPP1

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ENPP1/PC-1 gene K121Q polymorphism is associated with obesity in European adult populations: evidence from a meta-analysis involving 24,324 subjects.PMID 21565692Read ↗

New polymorphism of ENPP1 (PC-1) is associated with increased risk of type 2 diabetes among obese individuals.Semantic proximity Read ↗

Gender differences in the relationship of ENPP1/PC-1 variants to obesity in a Turkish population.Semantic proximity Read ↗

The ENPP1 K121Q polymorphism is associated with type 2 diabetes in European populations: evidence from an updated meta-analysis in 42,042 subjects.Semantic proximity Read ↗

No evidence of association of ENPP1 variants with type 2 diabetes or obesity in a study of 8,089 U.K. Caucasians.Semantic proximity Read ↗

The ENPP1 K121Q polymorphism is not associated with type 2 diabetes or obesity in the Chinese Han population.Semantic proximity Read ↗

Association of ENPP1 (PC-1) K121Q polymorphism with obesity-related parameters in subjects with metabolic syndrome.Semantic proximity Read ↗

Association of K121Q polymorphism in ENPP1 (PC-1) with BMI in Caucasian and African-American adults.Semantic proximity Read ↗

Obesity risk associated with the K121Q polymorphism of the glycoprotein PC-1 gene.Semantic proximity Read ↗

Association of the ENPP1 K121Q polymorphism with susceptibility to type 2 diabetes in different populations: evidence based on 40 studies.Semantic proximity Read ↗

The Q121 variant of ENPP1 may protect from childhood overweight/obesity in the Italian population.Semantic proximity Read ↗

The ENPP1 K121Q polymorphism is associated with type 2 diabetes and related metabolic phenotypes in a Taiwanese population.Semantic proximity Read ↗

The Q121/Q121 genotype of ENPP1/PC-1 is associated with lower BMI in non-diabetic whites.Semantic proximity Read ↗

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