Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

ALS: a disease of motor neurons and their nonneuronal neighbors.

Neuron - 5 Oct 2006

Boillée Séverine, Vande Velde Christine, Cleveland Don W

Abstract excerpt

Amyotrophic lateral sclerosis is a late-onset progressive neurodegenerative disease affecting motor neurons. The etiology of most ALS cases remains unknown, but 2% of instances are due to mutations in Cu/Zn superoxide dismutase (SOD1). Since sporadic and familial ALS affects the same neurons with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amyotrophic Lateral Sclerosis
Share to Axonal Transport
Share to Cell Death

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Inflammation

Share to Motor Neurons

Share to Neuroglia

Share to Superoxide Dismutase

Share to Superoxide Dismutase-1

Source

Identifiers

PMID: 17015226
DOI: 10.1016/j.neuron.2006.09.018

Genes

SOD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17015226-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

ALS: a disease of motor neurons and their nonneuronal neighbors.PMID 17015226Read ↗

Amyotrophic lateral sclerosis: from current developments in the laboratory to clinical implications.Semantic proximity Read ↗

Non-cell autonomous toxicity in neurodegenerative disorders: ALS and beyond.Semantic proximity Read ↗

Advances and challenges in understanding the multifaceted pathogenesis of amyotrophic lateral sclerosis.Semantic proximity Read ↗

Amyotrophic lateral sclerosis: all roads lead to Rome.Semantic proximity Read ↗

Amyotrophic lateral sclerosis: pathogenesis.Semantic proximity Read ↗

Pathophysiology of neurodegeneration in familial amyotrophic lateral sclerosis.Semantic proximity Read ↗

Early pathogenesis in the adult-onset neurodegenerative disease amyotrophic lateral sclerosis.Semantic proximity Read ↗

Novel therapeutic targets for amyotrophic lateral sclerosis.Semantic proximity Read ↗

Amyotrophic Lateral Sclerosis: New Insights into Underlying Molecular Mechanisms and Opportunities for Therapeutic InterventionSemantic proximity Read ↗

Molecular biology of amyotrophic lateral sclerosis: insights from genetics.Semantic proximity Read ↗

State of the art and the dark side of amyotrophic lateral sclerosisSemantic proximity Read ↗

Necroptosis Drives Motor Neuron Death in Models of Both Sporadic and Familial ALSSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.