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Article

Adipokines and aging.

Journal of atherosclerosis and thrombosis - 1 Jan 2011

Arai Yasumichi, Takayama Michiyo, Abe Yukiko, Hirose Nobuyoshi

Abstract excerpt

Dysregulation of adipose tissue-derived bioactive molecules, termed adipokines, is recognized as common ground for insulin resistance and metabolic syndrome associated with obesity. However, adipokine dysregulation is paradoxically associated with lipodystrophy and lipoatrophy with aging. In familial partial lipodystrophic syndromes and Hutchinson-Gilford progeria syndrome, both of which are caused by mutations...

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Identifiers

PMID: 21551960
DOI: 10.5551/jat.7039

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LMNA

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