Article
Role of hnRNP-A1 and miR-590-3p in neuronal death: genetics and expression analysis in patients with Alzheimer disease and frontotemporal lobar degeneration.
Rejuvenation research - 1 Jun 2011
Villa Chiara, Fenoglio Chiara, De Riz Milena, Clerici Francesca, Marcone Alessandra, Benussi Luisa, Ghidoni Roberta, Gallone Salvatore, Cortini Francesca, Serpente Maria, Cantoni Claudia, Fumagalli Giorgio, Martinelli Boneschi Filippo, Cappa Stefano, Binetti Giuliano, Franceschi Massimo, Rainero Innocenzo, Giordana Maria Teresa, Mariani Claudio, Bresolin Nereo, Scarpini Elio, Galimberti Daniela
Abstract excerpt
An association study of heterogeneous nuclear ribonucleoprotein (hnRNP)-A1 was carried out in a population of 274 patients with frontotemporal lobar degeneration (FTLD) and 287 with Alzheimer disease (AD) as compared with 344 age- and gender-matched controls. In addition, we evaluated expression levels of hnRNP-A1 and its regulatory microRNA (miR)-590-3p in blood cells from patients and controls. A statistically...
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