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Article

Primate-specific miR-603 is implicated in the risk and pathogenesis of Alzheimer's disease.

Aging - 1 Feb 2016

Zhang Chi, Lu Jie, Liu Bing, Cui Qinghua, Wang Yun

Abstract excerpt

Alzheimer's disease (AD) is a serious neurodegenerative disease, and microRNAs (miRNAs) have been linked to its pathogenesis. miR-603, a novel primate-specific miRNA and an intronic miRNA of a human brain highly expressed gene KIAA1217, is implicated in the risk and pathogenesis of AD. The rs11014002 single nucleotide polymorphism (SNP) (C/U), which locates in miR-603 precursor (pre-miR-603), exhibits a...

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Identifiers

PMID: 26856603
DOI: 10.18632/aging.100887
PMCID: PMC4789582

Genes

LRPAP1
LRP1
RND1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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