Article
Heterogeneous immune cell composition in patients with combined immunodeficiency.
Frontiers in immunology - 1 Jan 2026
Pérez-Caraballo Jareb J, Roark Colleen M, Dobrose Megan M, Van den Rym Ana, Staines-Boone Aidé Tamara, Salazar-Galvez Yuridia, Gomez-Hernandez Noemi, Cui Jian, Brown Lauren E, Zhen Xin, Lugo Reyes Saul O, Blancas-Galicia Lizbeth, de la Calle-Martín Óscar, Mohammed Reem, Pérez de Diego Rebeca, Martínez-Barricarte Rubén
Abstract excerpt
Introduction: Combined immunodeficiencies (CIDs) are a severe class of inborn errors of immunity characterized by defective T cell development and function, often accompanied by impaired humoral and natural killer (NK) cell responses. Despite their shared clinical classification, the immunological heterogeneity within CIDs remains incompletely understood. This study aims to characterize the immune cell landscape...
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