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Article

famCNV: copy number variant association for quantitative traits in families.

Bioinformatics (Oxford, England) - 1 Jul 2011

Eleftherohorinou Hariklia, Andersson-Assarsson Johanna C, Walters Robin G, El-Sayed Moustafa Julia S, Coin Lachlan, Jacobson Peter, Carlsson Lena M S, Blakemore Alexandra I F, Froguel Philippe, Walley Andrew J, Falchi Mario

Abstract excerpt

UNLABELLED: A program package to enable genome-wide association of copy number variants (CNVs) with quantitative phenotypes in families of arbitrary size and complexity. Intensity signals that act as proxies for the number of copies are modeled in a variance component framework and association with traits is assessed through formal likelihood testing. AVAILABILITY AND IMPLEMENTATION: The Java package is made...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21546396
DOI: 10.1093/bioinformatics/btr264
PMCID: PMC3117380

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