Unique Features of HIV-1 Spread through T Cell Virological Synapses

Abstract excerpt

The spread of viral infections can be initiated by the release of cell-free virus particles that infect at a distance or via cell-associated virus, which can promote the direct transmission of viruses between adjacent cells. In the case of human immunodeficiency virus type 1 (HIV-1), cell–cell contact has been found to enhance infection through specialized structures called virological synapses (VS). Cell–cell...