Article
Relationship between clotting activity and phosphatidylserine expression on erythrocyte membranes in polycythemia vera patients with the JAK2 V617F mutation.
Archives of physiology and biochemistry - 1 Oct 2011
Fujita Hiroshi, Sakuma Ryoko, Tomiyama Junji, Hamaki Tamae, Ohwada Akira, Nishimura Shigeko
Abstract excerpt
INTRODUCTION: Polycythemia vera (PV) accompanies the clinical course of thrombosis. Phosphatidylserine (PS) expression on the plasma membrane has been known to be one of place where the coagulation system activates. We studied the relationship between clotting factor activity and PS expression on the erythrocyte membrane in patients with erythrocytosis. METHODS: The coagulation test and PS expression in 23...
Topics
- Adult
- Aged
- Annexin A5
- Blood Coagulation
- Blood Coagulation Factors
- Erythrocyte Membrane
- Female
- Flow Cytometry
- Humans
- Janus Kinase 2
- Male
- Middle Aged
- Mutation
- Phosphatidylserines