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Article

On being the right size: the impact of population size and stochastic effects on the evolution of drug resistance in hospitals and the community.

PLoS pathogens - 1 Apr 2011

Kouyos Roger D, Abel Zur Wiesch Pia, Bonhoeffer Sebastian

Abstract excerpt

The evolution of drug resistant bacteria is a severe public health problem, both in hospitals and in the community. Currently, some countries aim at concentrating highly specialized services in large hospitals in order to improve patient outcomes. Emergent resistant strains often originate in health care facilities, but it is unknown to what extent hospital size affects resistance evolution and the resulting...

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Identifiers

PMID: 21533212
DOI: 10.1371/journal.ppat.1001334
PMCID: PMC3077359

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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