Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cytogenetic and Immunohistochemical Evidence for the Germ Cell Origin of a Subset of Acute Leukemias Associated With Mediastinal Germ Cell Tumors

7 Feb 1990

Abstract excerpt

Most acute leukemias occurring in patients with mediastinal germ cell tumors (MGCTs) appear to be primary rather than therapy-related; however, no data have been obtained to date to confirm the hypothesized germ cell origin of the leukemias in this syndrome. We identified six male patients with this syndrome treated at Memorial Sloan-Kettering Cancer Center: in all six, the leukemia was studied...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Testicular diseases and treatments

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 2153216
DOI: 10.1093/jnci/82.3.221

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cytogenetic and Immunohistochemical Evidence for the Germ Cell Origin of a Subset of Acute Leukemias Associated With Mediastinal Germ Cell TumorsPMID 2153216Read ↗

Hematopoietic precursor cells within the yolk sac tumor component are the source of secondary hematopoietic malignancies in patients with mediastinal germ cell tumorsSemantic proximity Read ↗

Concurrent Primary Mediastinal Germ Cell Tumor and Acute Myeloid Leukemia: Case Report of Sustained Remission and Review of the LiteratureSemantic proximity Read ↗

A Clinicopathologic and Molecular Analysis of 34 Mediastinal Germ Cell Tumors Suggesting Different Modes of Teratoma DevelopmentSemantic proximity Read ↗

The clonal nature of mediastinal germ cell tumors and acute myelogenous leukemiaSemantic proximity Read ↗

Germ cell tumors and associated hematologic malignancies evolve from a common shared precursor.Semantic proximity Read ↗

Genetic analysis of mediastinal nonseminomatous germ cell tumors in children and adolescentsSemantic proximity Read ↗

Acute Myelogenous Leukemia After Treatment for Malignant Germ Cell Tumors in ChildrenSemantic proximity Read ↗

Primary mediastinal germ cell tumor and clonally related and unique hematologic neoplasms with i(12p) and TP53 mutation: A report of two cases.Semantic proximity Read ↗

Association between mediastinal germ cell tumors and hematologic malignancies: An updateSemantic proximity Read ↗

The absence of FOXA2 and HNF1β expression in vasculogenic mesenchymal lesions of germ cell origin suggests an evolutionary pathway similar to that of sarcomatoid yolk sac tumor.Semantic proximity Read ↗

Acquired isochromosome 12p, somatic TP53 and PTEN mutations, and a germline ATM variant in an adolescent male with concurrent acute megakaryoblastic leukemia and mediastinal germ cell tumor.Semantic proximity Read ↗

TERATOMA WITH MALIGNANT TRANSFORMATION: DIVERSE MALIGNANT HISTOLOGIES ARISING IN MEN WITH GERM CELL TUMORSSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.