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Large-scale recombinant adeno-associated virus production

15 Apr 2011

Abstract excerpt

Since recombinant adeno-associated virus (rAAV) was first described as a potential mammalian cell transducing system, frequent reports purportedly solving the problems of scalable production have appeared. Yet few of these processes have enabled the development of robust and economical rAAV production. Two production platforms have emerged that have gained broad support for producing both research and clinical...

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PMID: 21531790
DOI: 10.1093/hmg/ddr141

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