Article
Association of specific genotypes in metastatic suppressor HTPAP with tumor metastasis and clinical prognosis in hepatocellular carcinoma.
Cancer research - 1 May 2011
Ren Ning, Wu Jin-Cai, Dong Qiong-Zhu, Sun Hai-Jing, Jia Hu-Liang, Li Guo-Cai, Sun Bing-Sheng, Dai Chun, Shi Jiong, Wei Jin-Wang, Sheng Yuan-Yuan, Zhou Hai-Jun, Ye Qing-Hai, Qin Lun-Xiu
Abstract excerpt
The phosphatidic acid phosphatase HTPAP has been defined as a metastatic suppressor of hepatocellular carcinoma (HCC), but little is known about its function or potential applications as a prognostic marker. In this study, we analyzed patterns of HTPAP genetic variation and gene expression in 864 patients who underwent HCC resection, assessing these patterns for correlations to tumor metastasis potential....
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