Article
Identification of haptoglobin alpha-2FF variants in mid-trimester maternal serum as potential markers for Down syndrome.
Applied and theoretical electrophoresis : the official journal of the International Electrophoresis Society - 1 Jan 1990
Myrick J E, Caudill S P, Hubert I L, Robinson M K, Adams M J, Pueschel S M
Abstract excerpt
Exploratory protein analysis in mid-trimester maternal sera by 2-dimensional electrophoresis and image analysis was performed to determine the differences between mothers carrying fetuses with Down syndrome (DS) and control mothers. Nine haptoglobin alpha-1 and alpha-2 (Hp1 and Hp2) variants were detected. Three apparent isoforms of the Hp2FF protein having the same relative charge but different Mr's were...
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