Article
Identification of haptoglobin alpha-2FF variants in mid-trimester maternal serum as potential markers for Down syndrome.
Applied and theoretical electrophoresis : the official journal of the International Electrophoresis Society - 1 Jan 1990
Myrick J E, Caudill S P, Hubert I L, Robinson M K, Adams M J, Pueschel S M
Abstract excerpt
Exploratory protein analysis in mid-trimester maternal sera by 2-dimensional electrophoresis and image analysis was performed to determine the differences between mothers carrying fetuses with Down syndrome (DS) and control mothers. Nine haptoglobin alpha-1 and alpha-2 (Hp1 and Hp2) variants were...
Topics
- Age Factors
- Down Syndrome
- Electrophoresis, Gel, Two-Dimensional
- Female
- Fetus
- Genetic Markers
- Genetic Variation
- Haptoglobins
- Humans
- Molecular Weight
- Pregnancy
- Pregnancy Trimester, Second