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Amniotic Fluid Proteome Analysis from Down Syndrome Pregnancies for Biomarker Discovery

11 May 2010

Abstract excerpt

Down syndrome (DS) is an anomaly caused by an extra chromosome 21, and it affects 1 in 750 live births. Phenotypes include cognitive impairment, congenital defects, and increased risk for several diseases such as Alzheimer's disease and leukemia. Current DS-screening tests subject many women to invasive procedures for accurate diagnosis due to insufficient specificity. Since amniotic fluid (AF) surrounds the...

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Down syndrome and intellectual disability research
Gestational Trophoblastic Disease Studies
Prenatal Screening and Diagnostics

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 20459121
DOI: 10.1021/pr100088k

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Amniotic Fluid Proteome Analysis from Down Syndrome Pregnancies for Biomarker DiscoveryPMID 20459121Read ↗

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