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Article

Screening of ACTN4 and TRPC6 mutations in a Chinese cohort of patients with adult-onset familial focal segmental glomerulosclerosis.

Contributions to nephrology - 1 Jan 2013

Zhang Qianying, Ma Jun, Xie Jingyuan, Wang Zhaohui, Zhu Bin, Hao Xu, Yang Li, Ren Hong, Chen Nan

Abstract excerpt

OBJECTIVES: Familial focal segmental glomerulosclerosis (FSGS) has been widely reported as having an underlining genetic component to its pathogenesis. Recently, mutations in TRPC6 and ACTN4 were identified to be associated with familial FSGS, however few studies have reported the mutation rates of these two genes in Chinese familial FSGS patients. The aim of this study was to determine the prevalence of TRPC6...

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Source

Identifiers

PMID: 23689571
DOI: 10.1159/000348471

Genes

ACTN4
TRPC6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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